Acanthosis nigricans disease

An acanthosis nigricans is a skin condition when one or more areas of the skin change color to dark and thickened. Often, the part of the skin that is affected by the Axrikans accordion feels like velvet when it is palpable.

The acanthosis nigricans is more commonly found in those with darker skin tones. This disorder is not contagious. However, this condition needs to be evaluated to determine the cause. This is because the disease is a symptom that can be caused by other diseases. 

Acanthosis nigricans disease | Diseasezero


Causes of the Acanthosis nigricans


The cause of the acanthosis nigricans has not been defined with certainty. There are nine different types of known acanthosis, namely:

  • Obesity Associated Akantosis. It is associated with excessive weight and is the most common type of acanthosis nigricans activists.

  • More often found in adults. Generally, this type is associated with insulin resistance. This condition is also often used as a marker for metabolic syndrome in child patients.

  • Syndromic acanthosis nigricans. An acanthosis of the Oxrikans associated with the various syndrome, such as lupus erythematosus, Prader-Willi syndrome, Acromegaly, gigantism, and others.

  • Aural acanthosis. It is commonly found in dark-skinned and is of African racial descent. These skin lesions are often found on the backs of the hands and feet, as well as the knuckles.

  • Unilateral and acanthosis nigricans. Lesions are found on one side of the body and are believed to be lowered by autosomal dominant.

  • Generalized A... This condition is rarely found and usually occurs in children.

  • Familial acanthosis nigricans. This acanthosis nigricans is derived autosomal dominant.

  • Drug-induced acanthosis nigricans. This type of one is rarely found. It can be triggered by the consumption of drugs such as nicotinic acid, insulin, systemic corticosteroid, and Diethylstilbestrol.

  • Malignant of the former acanthosis. This condition is related to cancer or violence. Malignant is most often associated with adenocarcinomas from the gastrointestinal tract, and generally gastric adenocarcinoma (a malignant type).

It is always a good idea to be cautious when the growth of the acanthosis nigricans activists develops rapidly, and is found in areas that are not common, are wide, and cause symptoms.

  • A Mixed type of acanthosis. It is a mixture of the above types.

Diagnosis of the acanthosis nigricans


To determine the diagnosis of the Axrikans acanthosis, a doctor should be done a complete evaluation. Evaluation is done through:

  • A detailed medical interview to explore information about the history of the disease, signs, and symptoms, and family history.
  • Physical examination, by looking at the skin lesions directly. Generally, the affected skin will appear blackish compared to surrounding skin and thicker texture.
  • Supporting examination, conducted to help determine the cause. For example, there will be a blood sugar test to ensure the suspicion of insulin resistance.

Symptoms of acanthosis nigricans


Several signs can be experienced by the sufferer of the disease, namely:

  • Skin lesions are blackish, accompanied by thickening of the skin, and can feel like velvet in the feeling.
  • Often black lesions are found in the crease area, such as the groin, armpit, and back neck.
  • Sometimes accompanied by itching complaints.
  • It can be accompanied by skin tag (a kind of tissue grows) on skin lesions or areas surrounding the lesions.
  • Acanthosis of the dissemination caused by violence is no different from its appearance from the other cause.

Acanthosis nigricans Treatment


There is no specific treatment that targets the negligent activists. Treatment is generally targeted to handle the backdrop of the cause of the Axrikans acanthosis.

Therefore, it is very important to know the cause and handle the cause of the Axrikans acanthosis. For example, often these circumstances are caused by obesity and insulin resistance. Thus, the handling should also be a way of weight loss and correction of hyperinsulinemia.

Some other types of handling suggested are the use of topical drugs such as keratolytic agents and triple-Combination depigmenting cream (using Tretinoin, hydroquinone, and Fluocinolone acetonide) at night accompanied by the use of a curtain Solar during the day.

Also, some types of drinking medications can be beneficial. For example Etretinate, isotretinoin, metformin, and fish oil. To overcome the thickened skin, it can be advised of dermabrasion action and laser therapy.

Prevention of acanthosis nigricans


There have been no definite precautions to avoid Axrikans activists. One of the prevention that can be controlled is to maintain the bodyweight to keep it normal. When the skin conditions are blackened and thickened, check into the doctor immediately for proper handling as early as possible.

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